Ischemic Heart Disease (IHD)

 

  • Background

    • IHD (aka coronary heart disease, coronary artery disease) is the presence of symptoms or signs of cardiac ischaemia.
    • Commonest ischaemia cause is atherosclerosis, the formation of lipid-laden plaques in coronary artery walls.
    • Symptoms occur when plaques (a) grow and obstruct the vessel, causing angina, or (b) rupture and form a thrombus, occluding the vessel and causing an acute coronary syndrome.
  • Presentation

    IHD can present with angina or acute coronary syndrome (ACS).

  • Risk factors

    Modifiable RFs:

    • HTN
    • Dyslipidaemia: ↑TC, ↑TC:HDL ratio, ↑LDL.
    • Diabetes
    • Smoking
    • Excess alcohol
    • Obesity

    Fixed RFs:

    • Age
    • Male
    • South Asian ethnicity.
    • Medical history of atheroma: MI, stroke, or PVD.
    • Family history: MI in 1st degree relative, male < 55 years, female < 65 years.

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